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To prepare and submit Piperazine citrate elixir BP (20 ml)

To prepare and submit Piperazine citrate elixir BP (20 ml)

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Aim:

To prepare and submit Piperazine citrate elixir BP (20 ml)

Requirements:

Piperazine citrate, chloroform spirit, orange oil, syrup, Glycerin, beaker, stirrer, spatula, measuring cylinder, and purified water.

Principle:

Elixirs are clear, flavored, sweetened hydroalcoholic liquid preparations for oral administration. The Percentage of alcohol varies from 4 to 40 %. In this elixirs Propylene glycol, ethanol, and glycerol these are all acts a vehicle and co-solvent to increase the solubility of poorly soluble ingredients. Chloroform spirit acts as a preservative. Invert syrup acts as a sweetening agent.

Formulation Table :

                         Ingredients            Quantity Prescribed

                   (1000 ml)

 Quantity taken
       (20 ml)
                    Piperazine Citrate                                 180 gm
                  Chloroform spirit                                 5 ml
                       Glycerin                                 100 ml
                    Orange oil                                 0.25 ml
                        Syrup                                 500 ml
               Purified water up to                                1000 ml

Note : All calculation will be done by student itself & the quantities of ingredients are tentative and depends on the experiment performer.

Procedure

  •  Piperazine citrate is dissolved in small amount of purified water.
  • Orange oil, glycerin, syrup and chloroform spirit is mixed.
  • Sufficient volume is added to produce the final volume.

LABEL:

Use:

Anthelmentic

Storage

Stored in a well closed container at a temperature not exceeding 25 0C.

 

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