Anatomy & Histology(Human Anatomy & Physiology)
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Click Here to Download Notes: Pharm. D. 1st Year Human Anatomy & Physiology Hand Written Notes Complete
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Substrate The substrate plays the most important part in determining the rate of the reaction. This is because the nucleophile attacks from the back of the substrate, thus breaking the carbon-leaving group bond and forming the carbon-nucleophile bond. Therefore, to maximize the rate of the SN2 reaction, the back of the substrate must be as …